Transcription of the interview with Charles-Ferdinand Nothomb, Belgian Foreign Minister from 1980 to 1981 and President of the Chamber of Representatives from 1979 to 1980 and from 1988 to 1995, carried out by the Centre Virtuel de la Connaissance sur l’Europe (CVCE) on 2 June 2010 on the CVCE’s premises at the Château de Sanem. Conducted by Hervé Bribosia, Research Coordinator at the CVCE, this interview complements the one conducted on 9 July 2002 and particularly focuses on the European dimension of Nothomb’s posts as Foreign Minister (1980–1981), Interior Minister (1981–1986) and President of the Chamber of Representatives (1979–1980; 1988–1995); it also covers Euro-Mediterranean and Euro-Arab relations and Belgium’s role in the European integration process.